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Robert A Cramer Selected Research

Ergosterol (Lumisterol)

11/2014ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence.
2/2012Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter.
1/2012Coordination of hypoxia adaptation and iron homeostasis in human pathogenic fungi.
12/2011SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus.

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Robert A Cramer Research Topics

Disease

20Infections
01/2022 - 06/2006
20Hypoxia (Hypoxemia)
01/2021 - 11/2008
10Mycoses (Diseases, Fungus)
01/2020 - 04/2011
9Invasive Pulmonary Aspergillosis
01/2022 - 07/2011
5Aspergillosis
01/2022 - 06/2006
4Inflammation (Inflammations)
12/2021 - 09/2014
4Starvation
10/2014 - 03/2006
3Invasive Fungal Infections
01/2017 - 06/2007
2Cystic Fibrosis (Mucoviscidosis)
01/2022 - 12/2020
2Disease Progression
01/2021 - 08/2017
2Lung Diseases (Lung Disease)
01/2021 - 12/2020
2Hypersensitivity (Allergy)
12/2018 - 04/2003
2Neoplasms (Cancer)
11/2018 - 02/2010
2HIV Infections (HIV Infection)
01/2017 - 05/2012
1Pulmonary Aspergillosis
01/2022
1Coinfection
10/2021
1Hemorrhage
01/2020
1Melanoma (Melanoma, Malignant)
11/2018
1Obesity
01/2018
1Borrelia Infections
12/2016
1Lyme Disease (Disease, Lyme)
12/2016
1Acquired Immunodeficiency Syndrome (AIDS)
02/2010

Drug/Important Bio-Agent (IBA)

11Oxygen (Dioxygen)IBA
01/2022 - 07/2011
7IronIBA
12/2015 - 12/2011
6CytokinesIBA
01/2021 - 04/2013
6Pharmaceutical PreparationsIBA
01/2020 - 04/2011
6Proteins (Proteins, Gene)FDA Link
01/2017 - 04/2003
5Transcription Factors (Transcription Factor)IBA
12/2014 - 01/2012
4Ergosterol (Lumisterol)IBA
11/2014 - 12/2011
4TriazolesIBA
06/2014 - 12/2011
3AzolesIBA
12/2015 - 11/2008
3Sterol Regulatory Element Binding ProteinsIBA
12/2015 - 11/2008
2RNA (Ribonucleic Acid)IBA
01/2022 - 12/2017
2pimonidazoleIBA
01/2021 - 07/2011
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019 - 01/2013
2Glucose (Dextrose)FDA LinkGeneric
11/2018 - 12/2016
2GlucansIBA
11/2018 - 04/2013
2SterolsIBA
01/2017 - 02/2012
2TrehaloseIBA
01/2017 - 01/2017
2Adrenal Cortex Hormones (Corticosteroids)IBA
04/2013 - 07/2011
2EnzymesIBA
02/2012 - 06/2007
1Virulence Factors (Pathogenicity Factors)IBA
01/2022
1EchinocandinsIBA
01/2022
1Mitogen-Activated Protein KinasesIBA
12/2021
1Immunoglobulin E (IgE)IBA
01/2021
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
01/2021
1Peptide Initiation Factors (Initiation Factor)IBA
01/2021
1SoilIBA
01/2021
1Vitamin K 3 (Menadione)FDA Link
01/2021
1Fungal AntigensIBA
01/2020
1CarbohydratesIBA
12/2018
1Polysaccharides (Glycans)IBA
11/2018
1Macrophage Colony-Stimulating FactorIBA
11/2018
1AcetoinIBA
08/2017
1Diacetyl (Biacetyl)IBA
08/2017
1Oxidoreductases (Dehydrogenase)IBA
01/2017
1NADP (NADPH)IBA
01/2017
1Leukotriene B4IBA
01/2017
1Lactic Acid (Lactate)FDA LinkGeneric
12/2016
1SiderophoresIBA
03/2016
1Peptide Hydrolases (Proteases)FDA Link
03/2016
1Voriconazole (Vfend)FDA LinkGeneric
03/2016
1Triamcinolone (Aristocort)FDA Link
01/2016
1C-Type Lectins (C-Type Lectin)IBA
01/2015
1Interleukin-1 (Interleukin 1)IBA
01/2015
1ChemokinesIBA
01/2015
1Histidine KinaseIBA
12/2014
1Heme (Haem)IBA
11/2014
1NitratesIBA
11/2014
1DNA (Deoxyribonucleic Acid)IBA
11/2014
1ChromatinIBA
11/2014
1Metformin (Glucophage)FDA LinkGeneric
09/2014
1Protein Kinases (Protein Kinase)IBA
09/2014
1Adenosine Monophosphate (AMP)IBA
09/2014
1Chemokine CXCL1IBA
09/2014
1Arginine (L-Arginine)FDA Link
01/2013
1CarbonIBA
01/2013
1dectin 1IBA
01/2013
1alternative oxidaseIBA
04/2012
1Cytochromes c (Cytochrome c)IBA
04/2012
1NAD (NADH)IBA
02/2012
1Messenger RNA (mRNA)IBA
02/2012
1gamma-Aminobutyric Acid (GABA)IBA
02/2012
1ProteomeIBA
02/2012
1Ethanol (Ethyl Alcohol)IBA
07/2011
1Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))IBA
07/2011
1CalcineurinIBA
06/2007
1Anti-Infective Agents (Microbicides)IBA
06/2007
1Melanins (Melanin)IBA
04/2007
1GliotoxinIBA
06/2006
1NitrogenIBA
03/2006
1Biological ProductsIBA
04/2003

Therapy/Procedure

7Therapeutics
01/2022 - 06/2007
1Platelet Transfusion (Blood Platelet Transfusions)
01/2020
1Transplantation
05/2012
1Immunomodulation
02/2010
1Organ Transplantation
02/2010